[Baroreflex regulation of circulation in essential hypertension patients treated with anaprilin]

The effect of propranolol on the baroreceptor reflex and the main indices of the central hemodynamics in single (i. v.) and prolonged (per os) administration of the drug were studied in patients with essential hypertension. The hemodynamic effect of propranolol depended, to a large extent, on the initial value of the baroreflex and its time course during treatment. Possible mechanisms of the effect of propranolol on the baroreflex were discussed.