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Enzymatic and non-enzymatic transnitrosylation: "SCAN"ning the SNO-proteome
Tomohiro Nakamura1, Stuart A Lipton1
1Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Molecular Cell
|January 19, 2024
Abstract:
In a recent study in Cell, Zhou et al.1 propose enzymatic transfer of nitric-oxide (NO)-related species from SNO-CoA to target proteins involved in insulin signaling; this function comprises an SNO-CoA-Assisted Nitrosylase (SCAN).
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