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Updated: Jul 5, 2025

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Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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APLAID complicated with arrhythmogenic dilated cardiomyopathy caused by a novel PLCG2 variant
Tianjiao Wang1, Xinyu Wang2,1, Yiqun Teng1
1Department of Pediatrics, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, 314000, China.
Immunologic Research
|January 19, 2024
Abstract
No abstract available in PubMed .
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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
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