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Related Concept Videos

Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

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Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Related Experiment Video

Updated: Jul 5, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
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Imaging for Target Volume Definition and Response Assessment in Lung Cancer.

Dirk De Ruysscher, Wouter van Elmpt

    Progress in Tumor Research
    |January 20, 2024
    PubMed
    Summary

    Defining target volumes for radiotherapy is crucial. FDG-PET-CT aids in defining lymph node involvement and tumor extent, but its use for response assessment is limited due to false signals.

    Area of Science:

    • Radiotherapy and Medical Imaging
    • Oncology and Radiation Physics

    Background:

    • Accurate target volume definition is critical for effective radiotherapy planning.
    • Current standard is single-energy CT, but advanced imaging modalities offer improved characterization.

    Purpose of the Study:

    • To review the role of various imaging techniques in radiotherapy target volume definition.
    • To discuss the utility and limitations of FDG-PET-CT and other advanced CT techniques.

    Main Methods:

    • Review of current literature on imaging in radiotherapy.
    • Discussion of single-energy CT, FDG-PET-CT, 4D CT, and dual-energy CT.
    • Evaluation of response assessment criteria like RECIST.

    Main Results:

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  • FDG-PET-CT assists in defining gross tumor volume and lymph node involvement but has limitations for response assessment.
  • 4D CT and dual-energy CT provide insights into lung characteristics and tissue properties.
  • Assessing radiotherapy response via CT is challenging due to post-treatment changes.

    • Conclusions:

    • FDG-PET-CT is valuable for initial target delineation but not recommended for response assessment due to high false positive/negative rates.
    • Advanced CT techniques like dual-energy CT show promise for future tissue characterization.
    • Further research is needed for improved radiotherapy response assessment.