Jove
Visualize
Contact Us

Related Concept Videos

Galvanometer01:25

Galvanometer

2.2K
Common devices, including car instrument panels, battery chargers, and inexpensive electrical instruments, measure potential difference (voltage), current, or resistance using a d'Arsonval galvanometer. This electromechanical instrument is also known as a moving coil galvanometer.
The galvanometer consists of  two concave-shaped permanent magnets, providing a uniform radial magnetic field in the annular region. In the center, a pivoted coil of fine copper wire is placed in the uniform...
2.2K
Voltammetry: Factors Affecting Measurements01:21

Voltammetry: Factors Affecting Measurements

157
A current produced due to the redox reactions of the analyte at the working and auxiliary electrodes is called a faradaic current. The reaction can be divided into two types. The current generated due to the reduction of the analyte is called cathodic current, and it carries a positive charge. In contrast, the current produced by analyte oxidation is known as an anodic current, and it has a negative charge. The applied potential at the working electrode determines the faradaic current flow, and...
157
Electromotive Force02:36

Electromotive Force

26.3K
Electricity is generated by either electrons or ions flowing through a solution or a conducting medium. This flow of electrons or specifically electrical charge is defined as an electric current. When electrons move through a wire, they generate an electric current. It can be recalled  that in a redox reaction, electrons are lost and gained. In the spontaneous redox reaction of zinc  with copper, when zinc is immersed in a copper ion solution, a transfer of electrons from one...
26.3K
Standard Electrode Potentials03:02

Standard Electrode Potentials

43.9K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
43.9K
Voltammetry: Stripping Methods01:13

Voltammetry: Stripping Methods

232
Anodic Stripping Voltammetry (ASV), Cathodic Stripping Voltammetry (CSV), and Adsorptive Stripping Voltammetry (AdSV) are electrochemical techniques used to determine trace amounts of analytes in solution. These methods involve applying a potential to an electrode and measuring the resulting current.
Anodic Stripping Voltammetry (ASV)
ASV is used to determine metals and metalloids at trace levels. It involves two steps: deposition and stripping. First, a negative potential is applied to the...
232
Coulomb's Law01:30

Coulomb's Law

9.2K
Experiments with electric charges have shown that if two objects each have an electric charge, they exert an electric force on each other. The magnitude of the force is linearly proportional to the net charge on each object and inversely proportional to the square of the distance between them. The direction of the force vector is along the imaginary line joining the two objects and is dictated by the signs of the charges involved.
Newton's third law applies to the Coulomb force — the...
9.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perfect adaptation in eukaryotic gradient sensing using cooperative allosteric binding.

Physical review. E·2026
Same author

Intrinsic stochasticity in cell polarity and contact inhibition of locomotion.

ArXiv·2026
Same author

Divergence of detachment forces in the finite Voronoi model.

ArXiv·2026
Same author

Competing chemical gradients change chemotactic dynamics and cell distribution.

Physical review. E·2026
Same author

Controlling tissue size by active fracture.

Physical review. E·2026
Same author

NEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinity.

Cell reports·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 5, 2025

Utilizing Custom-designed Galvanotaxis Chambers to Study Directional Migration of Prostate Cells
08:45

Utilizing Custom-designed Galvanotaxis Chambers to Study Directional Migration of Prostate Cells

Published on: December 7, 2014

9.2K

Physical limits on galvanotaxis.

Ifunanya Nwogbaga1, A Hyun Kim1, Brian A Camley1,2

  • 1Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, USA.

Physical Review. E
|January 20, 2024
PubMed
Summary
This summary is machine-generated.

Eukaryotic cells use galvanotaxis to move towards wounds, guided by electric fields. Our model reveals molecular noise limits this cell navigation, suggesting sensor properties that enable efficient wound healing.

More Related Videos

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field
11:00

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

Published on: October 13, 2012

12.6K
Measurement of Cellular Chemotaxis with ECIS/Taxis
11:37

Measurement of Cellular Chemotaxis with ECIS/Taxis

Published on: April 1, 2012

14.8K

Related Experiment Videos

Last Updated: Jul 5, 2025

Utilizing Custom-designed Galvanotaxis Chambers to Study Directional Migration of Prostate Cells
08:45

Utilizing Custom-designed Galvanotaxis Chambers to Study Directional Migration of Prostate Cells

Published on: December 7, 2014

9.2K
A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field
11:00

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field

Published on: October 13, 2012

12.6K
Measurement of Cellular Chemotaxis with ECIS/Taxis
11:37

Measurement of Cellular Chemotaxis with ECIS/Taxis

Published on: April 1, 2012

14.8K

Area of Science:

  • Cell biology
  • Biophysics
  • Electrophysiology

Background:

  • Eukaryotic cells exhibit galvanotaxis, migrating in response to electric fields, a process crucial for wound healing.
  • The precise molecular mechanisms by which cells sense electric fields remain unidentified, with surface molecule redistribution via electrophoresis and electroosmosis as leading hypotheses.

Purpose of the Study:

  • To develop a biophysical model linking cell surface sensor redistribution to galvanotaxis.
  • To predict and test the universal dependence of galvanotactic directionality on electric field strength.
  • To investigate the impact of molecular noise and sensor properties on cellular electric field sensing.

Main Methods:

  • Development of a mathematical model using maximum likelihood estimation to connect sensor redistribution and galvanotaxis.
  • Analysis and comparison of experimental galvanotaxis data from various cell types (keratocytes, neural crest cells, granulocytes).
  • Modeling the influence of stochasticity from a finite number of sensors on galvanotactic accuracy.

Main Results:

  • A single universal curve accurately describes galvanotactic directionality across different cell types and field strengths.
  • Cellular galvanotactic directionality can be achieved with a small number of highly polarized sensors or a large number with moderate concentration changes.
  • Identified a trade-off between accuracy and variance in cells responding to rapidly fluctuating electric fields, consistent with molecular noise limitations.

Conclusions:

  • Stochasticity arising from the finite number of cell surface sensors fundamentally limits galvanotactic accuracy.
  • The model provides constraints on the physical properties of putative galvanotaxis sensor molecules.
  • The findings offer a framework for future experiments to identify the specific molecules responsible for cellular electric field sensing and galvanotaxis.