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Related Experiment Video

Updated: Jul 5, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
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Monkeypox Virus (MPXV) Infection: A Review.

Rosy Kumari1, Pooja Arya2, Surya Prakash Yadav3

  • 1Department of Genetics, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.

Infectious Disorders Drug Targets
|January 20, 2024
PubMed
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Monkeypox (MPXV) is a global health concern, with India reporting its first case. This review details MPXV transmission, symptoms, and prevention, highlighting Tecovirimat as a potential treatment.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Monkeypox (MPXV) outbreak declared a global emergency by WHO.
  • First MPXV-infected patient identified in India, necessitating urgent research.
  • MPXV presents distinct characteristics compared to smallpox.

Purpose of the Study:

  • To review the current status of the MPXV outbreak in India.
  • To discuss MPXV transmission, virulence factors, symptoms, and treatment options.
  • To outline preventive guidelines issued by the Indian Health Ministry.

Main Methods:

  • Literature review of MPXV research and outbreak data.
  • Analysis of MPXV transmission dynamics and affected demographics.
  • Evaluation of current and potential therapeutic interventions.
Keywords:
MPXVMonkeypoxsymptomtransmissiontreatment.virulence factorvirus

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Related Experiment Videos

Last Updated: Jul 5, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
12:00

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

10.3K
Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2
10:55

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Published on: April 10, 2009

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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3
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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

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Main Results:

  • MPXV disease differs from smallpox; individuals aged 30-40 are most susceptible.
  • Transmission occurs beyond high-risk groups, affecting diverse populations.
  • Tecovirimat shows promise, though specific MPXV antiviral agents are needed.

Conclusions:

  • Urgent development of effective antiviral agents targeting MPXV virulence factors is crucial.
  • Public health guidelines emphasize avoiding close contact with infected individuals and animals.
  • Continued monitoring and research are essential for managing the MPXV outbreak.