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Chronic Subdural Hematoma Drainage under Local versus General Anesthesia: Systematic Review and Meta-Analysis
Eva Liu1, Amy Zhou1, Natalie Tilbury1
1Department of Neurosurgery, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Insights
Local anesthesia (LA) for chronic subdural hematoma evacuation offers shorter operative times, reduced hospital stays, and fewer complications compared to general anesthesia (GA). This makes LA a favorable, less invasive option, particularly for elderly patients undergoing neurosurgery.
Area of Science:
- Neurosurgery
- Anesthesiology
- Evidence-based medicine
Background:
- Chronic subdural hematoma (CSDH) is a common neurosurgical condition requiring treatment, typically burr-hole drainage.
- Optimal anesthetic strategy for CSDH evacuation remains debated between general anesthesia (GA) and local anesthesia (LA).
- This systematic review and meta-analysis compare postoperative outcomes of CSDH evacuation under LA versus GA.
Approach:
- Systematic literature search conducted in MEDLINE, Embase, and PubMed up to November 2023.
- Included 12 studies with 1035 patients in the LA group and 699 patients in the GA group.
- Followed PRISMA guidelines for study screening and data synthesis.
Key Points:
- Local anesthesia (LA) group demonstrated significantly shorter operative times (mean difference: -29.28 minutes).
- LA group experienced significantly shorter length of admission (mean difference: -1.58 days).
- LA group showed a significantly lower rate of postoperative complications (OR: 0.38).
- No significant differences were observed in revision rates (OR: 0.77) or mortality (OR: 1.23) between LA and GA groups.
Conclusions:
- Local anesthesia (LA) offers significant advantages over general anesthesia (GA) for chronic subdural hematoma evacuation.
- Benefits include reduced operative time, shorter hospital stays, and fewer postoperative complications.
- LA presents a less invasive and potentially superior anesthetic alternative, especially for elderly patient populations.
Background:
Chronic subdural hematoma (CSDH) is one of the most frequently encountered neurosurgical conditions. Although the mainstay treatment of chronic subdural hematoma has been burr-hole drainage, no consensus yet exists on the optimal anesthetic strategy between general anesthesia (GA) and local anesthesia (LA). This systematic review compares postoperative outcomes after CSDH evacuation under LA and GA.
Methods:
A search was conducted in MEDLINE (1946 to November 2023), Embase (1974 to November 2023), and PubMed (up to November 2023). We followed the PRISMA guidelines to systematically screen studies.
Results:
Our literature search identified 629 studies, out of which 12 were included. There were 1035 patients in the LA group and 699 patients in the GA group. Our meta-analysis found that the LA group had significantly shorter operative time (mean difference, -29.28 minutes; P < 0.0001), length of admission (mean difference, -1.58 days; 95% confidence interval [CI], -2.40 to -0.76 days; P = 0.0002), and postoperative complications rate (odds ratio [OR], 0.38; 95% CI, 0.25-0.59; P < 0.0001) compared with GA. There was no significant difference between the 2 groups in revision rate (OR, 0.77; 95% CI, 0.39-1.51; P = 0.45) and mortality (OR, 1.23; 95% CI, 0.63-2.43; P = 0.55).
Conclusions:
In this meta-analysis, LA shows benefits in shorter operative time, shorter admission length, and fewer postoperative complications. This finding makes LA a less invasive alternative to GA, especially in elderly patients.
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