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Cardiovascular changes under the microgravity environment and the gut microbiome.

Ruqaiyyah Siddiqui1, Rizwan Qaisar2, Khulood Al-Dahash3

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Astronauts experience gut microbiome changes in space, impacting cardiovascular health. Modifying the gut microbiota could improve astronaut health and performance during space missions.

Keywords:
Cardiovascular changesGut microbiomeMicrogravityOrthostatic hypotensionSpace travel

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Area of Science:

  • Space medicine
  • Microbiology
  • Cardiovascular science

Background:

  • The gut microbiome is crucial for human health.
  • Spaceflight alters astronaut gut microbiota composition.
  • Space environments pose risks like microgravity, radiation, and unloading.

Purpose of the Study:

  • Evaluate the gut microbiome's link to cardiovascular disease in microgravity.
  • Review spaceflight-induced cardiovascular issues like orthostatic hypotension and arrhythmias.
  • Examine cellular alterations during spaceflight.

Main Methods:

  • Review of existing literature on spaceflight effects on the gut microbiome and cardiovascular system.
  • Analysis of reported physiological and cellular changes in astronauts.
  • Correlation assessment between gut microbiota and cardiovascular disease markers.

Main Results:

  • Space travel significantly impacts gut microbiota diversity and composition.
  • Microgravity and other spaceflight factors are associated with cardiovascular changes.
  • Gut microbiome alterations correlate with cardiovascular risks in astronauts.

Conclusions:

  • Gut microbiome modifications offer a potential strategy to enhance astronaut health and performance.
  • Understanding these gut-cardiovascular links is vital for future long-duration space missions.
  • Further research is needed to develop targeted interventions for astronaut well-being.