Unselected donor-derived hematopoietic stem cells boost for Chimeric Antigen Receptor T-cell associated
Eugenio Galli1, Maria Assunta Limongiello1, Elisabetta Metafuni1
1Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Abstract:
Hematological toxicity following Chimeric Antigen Receptor-T therapy in a patient with a prior allogeneic stem cell transplantation was resolved by the infusion of unselected donor-derived stem cell boost. Due to the donor's lymphocytes, the patient experienced a well-controlled flare-up of acute graft versus host disease.
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