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Updated: Jul 5, 2025

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
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Targeting Cysteine Oxidation in Thrombotic Disorders

Moua Yang1, Roy L Silverstein2,3

  • 1Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, 3 Blackfan Circle, CLS-924, Boston, MA 02115, USA.

Antioxidants (Basel, Switzerland)
|January 22, 2024
PubMed
Summary

Oxidative stress promotes thrombosis via cysteine oxidation. This review explores mechanisms involving CD36 and protein disulfide isomerase (PDI), highlighting therapeutic targets for limiting blood clots.

Keywords:
CD36cysteinenucleophilesoxidative stressplateletsprotein disulfide isomerasethrombosis

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