Microfoundations of Data-Driven Antimicrobial Stewardship Policy (ASP)

Area of Science:

• Health Services Research
• Infectious Diseases
• Public Health Policy

Background:

• Antimicrobial resistance necessitates effective antimicrobial stewardship programs (ASPs).
• Resource-constrained settings face unique challenges in implementing comprehensive ASPs.
• Existing frameworks may not adequately address the microfoundations of ASPs in low-resource environments.

Purpose of the Study:

• To introduce a comprehensive framework elucidating the microfoundations of data-driven ASPs.
• To specifically tailor this framework for resource-constrained settings.
• To guide the development, implementation, and assessment of ASPs in diverse environments.

Main Methods:

• Conceptualization of microfoundations into input, process, output, and outcome components.
• Integration of social and material dimensions in program evaluation.
• Focus on harmonizing technology, practices, values, and behaviors.

Main Results:

• A structured framework for understanding data-driven ASPs in resource-limited contexts.
• Emphasis on stakeholder engagement and resource utilization.
• Consideration of microbiological, clinical, and social impacts.

Conclusions:

• The proposed framework provides a holistic approach to ASPs in resource-constrained settings.
• It highlights the importance of interlinked components and multi-dimensional evaluation.
• Offers actionable insights for optimizing antimicrobial stewardship globally.