Data-Driven Insights into Labor Progression with Gaussian Processes

Tilekbek Zhoroev1,2, Emily F Hamilton1,3, Philip A Warrick1,4

  • 1Medical Research and Development, PeriGen Inc., Cary, NC 27518, USA.

PubMed

Clinicians routinely perform pelvic examinations to assess the progress of labor. Clinical guidelines to interpret these examinations, using time-based models of cervical dilation, are not always followed and have not contributed to reducing cesarean-section rates. We present a novel Gaussian process model of labor progress, suitable for real-time use, that predicts cervical dilation and fetal station based on clinically relevant predictors available from the pelvic exam and cardiotocography. We show that the model is more accurate than a statistical approach using a mixed-effects model. In addition, it provides confidence estimates on the prediction, calibrated to the specific delivery. Finally, we show that predicting both dilation and station with a single Gaussian process model is more accurate than two separate models with single predictions.

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