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Peters anomaly: An overview.

Arpita Khasnavis1,2, Merle Fernandes2

  • 1Academy for Eye Care Education, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Taiwan Journal of Ophthalmology
|January 22, 2024
PubMed
Summary
This summary is machine-generated.

Peters anomaly (PA) is a rare congenital corneal opacity. A novel selective endothelialectomy procedure offers a minimally invasive alternative to corneal transplants for managing PA.

Keywords:
Congenital corneal opacityPeters anomalykerato-irido-lenticular dysgenesispediatric penetrating keratoplasty

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Area of Science:

  • Ophthalmology
  • Genetics
  • Developmental Biology

Background:

  • Peters anomaly (PA) is a rare congenital corneal opacity.
  • It involves corneal opacities and adhesions due to anterior segment dysgenesis.
  • PA often presents with other ocular and systemic comorbidities.

Purpose of the Study:

  • To provide a comprehensive overview of Peters anomaly.
  • To describe its etiology, classification, pathophysiology, histopathology, clinical features, and management.
  • To highlight recent advancements in PA treatment.

Main Methods:

  • Literature review and synthesis of existing research on Peters anomaly.
  • Analysis of clinical features and diagnostic criteria.
  • Evaluation of current and novel management strategies, including selective endothelialectomy.

Main Results:

  • Peters anomaly is characterized by specific corneal defects and adhesions.
  • Multidisciplinary management is crucial due to associated comorbidities.
  • Selective endothelialectomy shows promise as a less invasive treatment option.

Conclusions:

  • Peters anomaly requires a specialized, team-based approach for optimal care.
  • Minimally invasive techniques like selective endothelialectomy are emerging as viable alternatives to traditional corneal transplantation.
  • Further research into PA's pathophysiology and treatment efficacy is warranted.