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Endoscopy in pediatric polyposis syndromes: why, when and how
Shlomi Cohen1, Warren Hyer2, Thomas Attard3
1Pediatric Gastroenterology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Hereditary polyposis syndrome (HPS) in children requires careful endoscopic management. Early diagnosis and surveillance using therapeutic endoscopy help prevent complications and malignancies.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Oncology
Background:
- Colonic polyps in children can indicate hereditary polyposis syndrome (HPS).
- HPS poses a high risk for intestinal and extra-intestinal malignancies.
- Effective management is crucial to prevent serious complications.
Purpose of the Study:
- To outline the management strategy for children diagnosed with HPS.
- To emphasize the role of therapeutic endoscopy in HPS care.
- To highlight the importance of a multidisciplinary approach.
Main Methods:
- Colonoscopy for polyp detection and characterization.
- Histological examination of polyps.
- Therapeutic endoscopy, including polypectomies with advanced techniques.
- Multidisciplinary team approach for comprehensive care.
Main Results:
- Management decisions are based on polyp number, distribution, and histology.
- Surveillance aims to manage symptoms, monitor polyp burden, and prevent complications.
- Therapeutic endoscopy is central to HPS management in children.
Conclusions:
- Children with HPS require vigilant surveillance and management.
- Advanced endoscopic techniques and polypectomy are key interventions.
- A multidisciplinary strategy is essential for optimal outcomes in pediatric HPS.
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