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Endoscopy in pediatric polyposis syndromes: why, when and how

Shlomi Cohen1, Warren Hyer2, Thomas Attard3

  • 1Pediatric Gastroenterology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

European Journal of Gastroenterology & Hepatology
|January 22, 2024
PubMed

Insights

Hereditary polyposis syndrome (HPS) in children requires careful endoscopic management. Early diagnosis and surveillance using therapeutic endoscopy help prevent complications and malignancies.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Oncology

Background:

  • Colonic polyps in children can indicate hereditary polyposis syndrome (HPS).
  • HPS poses a high risk for intestinal and extra-intestinal malignancies.
  • Effective management is crucial to prevent serious complications.

Purpose of the Study:

  • To outline the management strategy for children diagnosed with HPS.
  • To emphasize the role of therapeutic endoscopy in HPS care.
  • To highlight the importance of a multidisciplinary approach.

Main Methods:

  • Colonoscopy for polyp detection and characterization.
  • Histological examination of polyps.
  • Therapeutic endoscopy, including polypectomies with advanced techniques.
  • Multidisciplinary team approach for comprehensive care.

Main Results:

  • Management decisions are based on polyp number, distribution, and histology.
  • Surveillance aims to manage symptoms, monitor polyp burden, and prevent complications.
  • Therapeutic endoscopy is central to HPS management in children.

Conclusions:

  • Children with HPS require vigilant surveillance and management.
  • Advanced endoscopic techniques and polypectomy are key interventions.
  • A multidisciplinary strategy is essential for optimal outcomes in pediatric HPS.

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