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Immunohistochemistry: The Importance of Precision Ontology to Precision Oncology

Emina E Torlakovic1, Carol C Cheung2

  • 1Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan and Saskatchewan Health Authority, Saskatoon, SK.

Applied Immunohistochemistry & Molecular Morphology : AIMM
|January 22, 2024
PubMed
Abstract

No abstract available in PubMed .

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Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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