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Antimicrobial resistance crisis: could artificial intelligence be the solution?

Guang-Yu Liu1, Dan Yu2, Mei-Mei Fan1

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Military Medical Research
|January 23, 2024
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Summary

Novel antibiotics are urgently needed to combat antimicrobial resistance. Artificial intelligence (AI) is accelerating the discovery and development of new antibacterial drugs, offering a promising solution to this global health crisis.

Keywords:
AntibioticAntibiotic stewardshipAntimicrobial peptideArtificial intelligence (AI)Clinical developmentMachine learning (ML)Phage therapy

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Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Computational Biology

Background:

  • Antimicrobial resistance (AMR) poses a significant global health threat.
  • The development of novel antibiotics is slow, expensive, and has yielded limited new drugs since 2014.
  • The World Health Organization (WHO) has identified priority pathogens requiring urgent development of new antibacterial agents.

Conclusions:

  • Novel antibiotics are critically needed to address the growing threat of antimicrobial resistance.
  • Artificial intelligence is a transformative tool for accelerating the discovery and development pipeline of new antibacterial agents.
  • AI integration across various facets of antibacterial drug development offers a promising path forward in combating AMR.