Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.6K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K
The Thyroid Gland01:23

The Thyroid Gland

3.9K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.9K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

93
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
93
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

241
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
241

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond metastases: a mechanism-based guide to misleading ¹³¹I uptake on whole-body scintigraphy.

Annals of nuclear medicine·2026
Same author

Theranostic Approaches to Radioiodine-Refractory Differentiated Thyroid Cancer: A Narrative Review.

Cancers·2026
Same author

ProGRP dynamics as a prognostic predictor in advanced medullary thyroid carcinoma.

Clinical chemistry and laboratory medicine·2026
Same author

Dual tracer PET/CT imaging for a patient with lipoadenoma: what Choline missed but Trivehexin revealed.

European journal of nuclear medicine and molecular imaging·2026
Same author

Measurement of CYFRA 21-1 in Fine-Needle Washout of Cervical Lymph Nodes in Differentiated Thyroid Carcinoma: A Systematic Review and Meta-Analysis.

Acta cytologica·2026
Same author

Procalcitonin Doubling Time for Postoperative Monitoring of Medullary Thyroid Carcinoma: A Comparative Kinetic Analysis.

Clinical endocrinology·2026

Related Experiment Video

Updated: Jul 5, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

632

Integrated Diagnostics of Thyroid Nodules.

Luca Giovanella1,2, Alfredo Campennì3, Murat Tuncel4

  • 1Department of Nuclear Medicine, Gruppo Ospedaliero Moncucco SA, Clinica Moncucco, 6900 Lugano, Switzerland.

Cancers
|January 23, 2024
PubMed
Summary

This review discusses diagnostic tools for thyroid nodules, including ultrasound, scintigraphy, and fine-needle aspiration. It proposes integrating these methods to improve accuracy and reduce unnecessary surgeries for thyroid cancer.

Keywords:
cytopathologynuclear medicinethyroidthyroid stimulating hormoneultrasonography

More Related Videos

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
04:23

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

Published on: April 21, 2023

1.9K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

552

Related Experiment Videos

Last Updated: Jul 5, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
05:41

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

632
A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
04:23

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

Published on: April 21, 2023

1.9K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

552

Area of Science:

  • Endocrinology
  • Diagnostic Imaging
  • Oncology

Background:

  • Thyroid nodules are prevalent, especially in iodine-deficient areas.
  • Accurate diagnosis is crucial for appropriate patient management.
  • Current diagnostic tools have limitations, leading to potential overtreatment or delayed diagnosis.

Purpose of the Study:

  • To review and compare various diagnostic tools for thyroid nodules.
  • To propose a rational integration strategy for these tools.
  • To highlight methods for reducing unnecessary surgeries for indeterminate thyroid nodules.

Main Methods:

  • Comprehensive review of thyroid ultrasound (US) and its scoring systems.
  • Evaluation of thyroid scintigraphy for hyperfunctioning nodules.
  • Analysis of fine-needle aspiration cytology (FNAC) and its indeterminate rates.
  • Assessment of molecular imaging ([99mTc]Tc-MIBI, [18F]FDG) and artificial intelligence (AI) in diagnosis.

Main Results:

  • Ultrasonographic scoring aids in differentiating benign from malignant nodules.
  • Thyroid scintigraphy effectively identifies hyperfunctioning nodules, excluding malignancy.
  • Indeterminate FNAC results necessitate further investigation, often surgery.
  • [99mTc]Tc-MIBI and [18F]FDG molecular imaging show promise in avoiding unnecessary surgeries.

Conclusions:

  • A rational integration of diagnostic tools, guided by US risk stratification, is essential.
  • Thyroid scintigraphy is key for hyperfunctioning nodules, while US guides FNAC for non-toxic nodules.
  • Molecular imaging and AI hold potential for improving diagnostic accuracy and reducing surgical interventions for thyroid nodules.