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Published on: December 14, 2019
Surgical and Endoscopic Intervention for Chronic Pancreatitis in Children: The Kings College Hospital Experience
Renos M Jeropoulos1, Deepak Joshi2, Bashar Aldeiri1
1Department of Paediatric Surgery, Chelsea and Westminster Hospital, London SW10 9NH, UK.
Insights
Paediatric chronic pancreatitis (CP) is a rare condition requiring advanced diagnostics and treatments. Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) are key endoscopic tools, alongside surgery for complications.
Area of Science:
- Gastroenterology and Hepatology
- Pediatric Surgery
- Medical Imaging
Background:
- Paediatric chronic pancreatitis (CP) is a rare, debilitating condition.
- It often necessitates invasive diagnostic and therapeutic approaches.
- Management addresses primary causes like pancreaticobiliary malunion and secondary complications such as chronic pain.
Purpose of the Study:
- To review the diagnostic and therapeutic roles of endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) in pediatric CP.
- To highlight the increasing utilization of endoscopic interventions.
- To discuss the role of surgical interventions in managing CP and its complications.
Main Methods:
- Review of current literature and clinical practices regarding pediatric CP management.
- Emphasis on endoscopic techniques (ERCP, EUS) for diagnosis and therapy.
- Discussion of surgical interventions for ductal decompression and anatomical abnormalities.
Main Results:
- ERCP and EUS are established diagnostic tools in pediatric CP.
- Therapeutic applications of ERCP and EUS are gaining popularity.
- Surgical decompression effectively alleviates pancreatic duct hypertension.
- Surgery is also indicated for specific anatomical issues and complications like pseudocysts.
Conclusions:
- Endoscopic modalities (ERCP, EUS) are crucial in diagnosing and treating pediatric CP.
- Surgical interventions remain vital for specific complications and anatomical corrections.
- A multidisciplinary approach integrating endoscopic and surgical techniques optimizes outcomes for pediatric CP patients.
Abstract:
Paediatric chronic pancreatitis (CP) is a rare and debilitating pathology that often requires invasive diagnostics and therapeutic interventions either to address a primary cause such as a pancreaticobiliary malunion or to deal with secondary complications such as chronic pain. Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) are two endoscopic modalities that have an established diagnostic role in paediatric CP, and their therapeutic utilisation is increasing in popularity. Surgical decompression of the obstructed and dilated pancreatic duct plays a role in alleviating pancreatic duct hypertension, a common association in CP. Surgery equally has a role in certain anatomical abnormalities of the pancreaticobiliary draining system, or occasionally in some CP complications such as drainage of a symptomatic pancreatic pseudocyst.
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