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Long-Term Atrioventricular Block Following Valve Surgery: Electrocardiographic and Surgical Predictors
Jacopo Farina1, Mauro Biffi2, Gianluca Folesani3
1Cardiology Unit, Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria di Ferrara, 44124 Ferrara, Italy.
Insights
Patients undergoing valve surgery face a continuing risk of bradyarrhythmia requiring pacemaker implantation. Pre-operative conduction disease and combined valve interventions are key predictors for this long-term complication.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Bradyarrhythmia requiring pacemaker implantation can occur years after valve surgery.
- Predictors for late pacemaker implantation after valve surgery are not well understood.
Purpose of the Study:
- To investigate the incidence of pacemaker implantation at various follow-up times post-valve surgery.
- To identify predictors associated with pacemaker implantation in this patient cohort.
Main Methods:
- Retrospective study of 1046 patients undergoing valve surgery.
- Data collected from 2005 to 2010 at Bologna University Hospital.
Main Results:
- 11.4% of patients required pacemaker implantation during a 10 ± 4 year follow-up.
- Interventions on both atrioventricular valves predicted long-term pacemaker implantation (SHR 2.1).
- Preoperative atrioventricular conduction disease, including right bundle branch block (SHR 7.0), strongly predicted atrioventricular block.
Conclusions:
- A continuing risk of atrioventricular block requiring pacemaker implantation exists up to 12 months post-valve surgery.
- Pre-operative atrioventricular conduction disease and combined atrioventricular valve surgery are significant predictors of pacemaker implantation.
Background:
Bradyarrhythmia requiring pacemaker implantation among patients undergoing valve surgery may occur even after several years, with unclear predictors. Our aim was to investigate the incidence of pacemaker implantation at different follow-up times and identify associated predictors.
Methods:
We conducted a retrospective study evaluating 1046 consecutive patients who underwent valve surgery at the Cardiac Surgery Division of Bologna University Hospital from 2005 to 2010.
Results:
During 10 ± 4 years of follow-up, 11.4% of these patients required pacemaker implantation. Interventions on both atrioventricular valves independently predicted long-term pacemaker implantation (SHR 2.1, 95% CI 1.2-3.8, p = 0.014). Preoperative atrioventricular conduction disease strongly predicted long-term atrioventricular block, with right bundle branch block as the major predictor (SHR 7.0, 95% CI 3.9-12.4, p < 0.001), followed by left bundle branch block (SHR 4.9, 95% CI 2.4-10.1, p < 0.001), and left anterior fascicular block (SHR 3.9, 95% CI 1.8-8.3, p < 0.001).
Conclusion:
Patients undergoing valvular surgery have a continuing risk of atrioventricular block late after surgery until the 12-month follow-up, which was clearly superior to the rate of atrioventricular block observed at long-term. Pre-operative atrioventricular conduction disease and combined surgery on both atrioventricular valves are strong predictors of atrioventricular block requiring pacemaker implantation.
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