Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

372
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
372

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heart Failure Through the Lens of Complexity.

American journal of physiology. Heart and circulatory physiology·2026
Same author

GLP-1-Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes.

Diabetes, obesity & metabolism·2026
Same author

Cancer as a Hidden Catalyst: Rethinking Postoperative Atrial Fibrillation After Cardiac Surgery.

Journal of clinical medicine·2026
Same author

Robotic-Assisted Thoracic Surgery in the Immunotherapy Era: Navigating Altered Anatomy, Oncologic Precision, and the Future of Integrated Platforms.

Journal of clinical medicine·2026
Same author

Optimal Antithrombotic Therapy for Peripheral Artery Disease: A Systematic Review and Network Meta-Analysis.

Journal of the American Heart Association·2026
Same author

The Legacy of the First Valve: Outcomes of Redo Surgical Aortic Valve Replacement After Prior Transcatheter Versus Prior Surgical Aortic Valve Replacement-A Narrative Review.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jul 5, 2025

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
08:30

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

Published on: February 14, 2022

2.7K

Heart Transplantation.

Nikolaos Chrysakis1, Dimitrios E Magouliotis2, Kyriakos Spiliopoulos2

  • 1Department of Cardiology, University Hospital of Larissa, 41110 Larissa, Greece.

Journal of Clinical Medicine
|January 23, 2024
PubMed
Summary

Heart transplantation (HTx) is a critical treatment for advanced heart failure. Recent advancements in donor selection, rejection monitoring, and immunosuppression therapies are improving outcomes for this life-saving procedure.

Keywords:
complicationscontraindicationsheart failureheart transplantationindicationsxenotransplantation

More Related Videos

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.7K
Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

35.3K

Related Experiment Videos

Last Updated: Jul 5, 2025

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft
08:30

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

Published on: February 14, 2022

2.7K
Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.7K
Implantation of the Syncardia Total Artificial Heart
16:11

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

35.3K

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Immunology

Background:

  • Heart transplantation (HTx) is the final treatment option for end-stage heart failure.
  • Patient outcomes are influenced by factors including compatibility, graft quality, and post-operative care.
  • Organ allocation policies have been revised to prioritize critically ill patients.

Purpose of the Study:

  • To review current challenges and recent advancements in heart transplantation.
  • To discuss factors affecting HTx outcomes and contraindications.
  • To highlight novel therapies and techniques in the field.

Main Methods:

  • Clinically focused review of existing literature and data.
  • Analysis of factors influencing heart transplant success.
  • Discussion of recent technological and therapeutic innovations.

Main Results:

  • Key factors influencing HTx outcomes include ABO/HLA compatibility, graft size, ischemic time, patient age, and infections.
  • Updated UNOS policy aims to reduce waiting list mortality by prioritizing sicker patients.
  • Major complications include rejection, infection, neoplasms, and graft failure.

Conclusions:

  • Despite challenges, heart transplantation remains vital for advanced heart failure.
  • Recent innovations like xenotransplantation and new immunosuppressants show promise.
  • Ongoing research focuses on improving donor selection, monitoring, and treatment strategies.