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Updated: Jul 5, 2025

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Published on: July 9, 2016
Involvement of the Expression of G Protein-Coupled Receptors in Schizophrenia
Raluka Kalinovic1,2, Andrei Pascariu2, Gabriela Vlad2
1Doctoral School, University of Medicine and Pharmacy Victor Babes Timisoara, 300041 Timisoara, Romania.
Abstract:
The expression of GPCRs has been associated with schizophrenia, and their expression may induce morphological changes in brain regions responsible for schizophrenia and disease-specific behavioral changes. The articles included in this review were selected using keywords and databases of scientific research websites. The expressions of GPRs have different involvements in schizophrenia, some increase the risk while others provide protection, and they may also be potential targets for new treatments. Proper evaluation of these factors is essential to have a better therapeutic response with a lower rate of chronicity and thus improve the long-term prognosis.
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