Related Experiment Video
Updated: Jun 23, 2026
07:46
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
Published on: June 4, 2012
15.8K
Infective Endocarditis Due to Kingella kingae.
Raphael Joye1, Vladimir L Cousin1,2, Iliona Malaspinas1
1Pediatric Cardiology Unit, Department of Woman, Child, and Adolescent Medicine, Faculty of Medicine, Geneva University Hospitals, 1205 Geneva, Switzerland.
Microorganisms
|January 23, 2024
Summary
Kingella kingae endocarditis is a rare but severe infection, primarily affecting children. Advances in diagnostics improve detection, highlighting the need for understanding epidemiology and virulence factors for effective treatment.
Area of Science:
- Infectious Diseases
- Pediatric Cardiology
- Microbiology
Background:
- Kingella kingae endocarditis is an uncommon yet serious invasive infection.
- This condition predominantly affects the pediatric population.
- Recent diagnostic advancements include nucleic acid amplification testing and cardiac imaging.
Purpose of the Study:
- To synthesize current knowledge on Kingella kingae endocarditis.
- To cover epidemiological features, pathophysiology, complications, and therapy.
- To identify knowledge gaps and future research directions.
Main Methods:
- Comprehensive literature review.
- Synthesis of existing data on Kingella kingae endocarditis.
- Analysis of epidemiological trends, virulence, and treatment strategies.
Main Results:
- Kingella kingae endocarditis, though rare, presents significant clinical challenges.
- Improved diagnostic tools enhance early and accurate identification.
- Understanding pathogen-specific factors is key for therapeutic guidance.
Conclusions:
- A comprehensive understanding of Kingella kingae endocarditis is essential for effective management in both children and adults.
- Further research is needed to address identified knowledge gaps.
- Integrated approaches combining diagnostics and pathogen knowledge are crucial.
Related Concept Videos
01:25Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:18Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
01:29Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
01:21Myocarditis I: Introduction
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
01:23Rheumatic Heart Disease I: Introduction
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...