Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Total ischemic burden: pathophysiology and prognosis.

P F Cohn

    The American Journal of Cardiology
    |March 9, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Silent myocardial ischemia, often without pain, significantly impacts cardiac prognosis. Aggressive treatment is crucial for patients with a high burden of silent ischemic episodes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    External counterpulsation for the treatment of myocardial ischemia.

    Heart disease (Hagerstown, Md.)·2001
    Same author

    Medical treatment of silent myocardial ischemia.

    Heart disease (Hagerstown, Md.)·2001
    Same author

    Acute hemodynamic effects and angina improvement with enhanced external counterpulsation.

    Angiology·2001
    Same author

    The value of continuous ST segment monitoring in patients with unstable angina.

    European heart journal·2001
    Same author

    Direct coronary stenting without balloon or device pretreatment: acute success and long-term results.

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2001
    Same author

    EECP -- new data on possible mechanisms of action.

    European heart journal·2001

    Area of Science:

    • Cardiology
    • Ischemic Heart Disease

    Background:

    • Myocardial ischemia results from supply-demand imbalance.
    • Total ischemic burden includes both symptomatic and silent episodes.
    • Silent myocardial ischemia (SMI) episodes can occur at lower heart rates, suggesting vasoconstriction.

    Purpose of the Study:

    • To explore the clinical significance of silent myocardial ischemia.
    • To investigate the relationship between SMI and cardiac prognosis.
    • To determine if aggressive therapy is warranted for significant SMI.

    Main Methods:

    • Analysis of myocardial ischemia episodes, both symptomatic and silent.
    • Evaluation of prognostic impact of silent myocardial ischemia.
    • Correlation of SMI duration and frequency with cardiac events.

    Related Experiment Videos

    Main Results:

    • Silent myocardial ischemia may be clinically more significant than painful episodes.
    • SMI is associated with adverse prognosis in asymptomatic and post-infarction patients.
    • A direct relationship exists between SMI burden and cardiac events in unstable angina.

    Conclusions:

    • Silent myocardial ischemia significantly contributes to the total ischemic burden.
    • Aggressive therapeutic strategies may be necessary for patients with substantial silent myocardial ischemia.
    • Understanding and managing SMI is critical for improving cardiac outcomes.