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Related Experiment Video

Updated: Jul 5, 2025

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Published on: January 30, 2017

A Comprehensive Allele Specific Expression Resource for the Equine Transcriptome.

Harrison D Heath, Sichong Peng, Tomasz Szmatola

Biorxiv : the Preprint Server for Biology

|January 23, 2024

Summary

This summary is machine-generated.

This study presents an equine allele-specific expression (ASE) analysis using integrated sequencing data. The findings offer a valuable resource for understanding gene regulation in horses, aiding research into equine health and disease.

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Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

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Related Experiment Videos

Last Updated: Jul 5, 2025

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

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Published on: January 30, 2017

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Published on: November 28, 2018

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

Published on: May 11, 2017

Area of Science:

Genomics
Molecular Biology
Equine Science

Background:

Allele-specific expression (ASE) analysis offers detailed insights into cis-regulatory mechanisms influencing gene expression.
Understanding ASE is crucial for dissecting gene regulation variability.

Approach:

Integrated analysis of long- and short-read RNA sequencing data from four healthy Thoroughbred horses (2 mares, 2 stallions).
Incorporation of histone modification data across nine distinct equine tissues.
Development of a comprehensive equine ASE resource.

Key Points:

The study establishes a foundational dataset for equine ASE.
Provides a molecular-level understanding of allelic imbalance in Thoroughbreds.
Highlights the utility of integrated genomic data for regulatory studies.

Conclusions:

The developed equine ASE resource is publicly accessible.
Facilitates future research into regulatory variation within equine tissues.
Enhances understanding of allelic imbalance in equine health and disease.