Global research trends and hotspots on tendon-derived stem cell: a bibliometric visualization study

Area of Science:

• Biomedical Engineering
• Regenerative Medicine
• Cell Biology

Background:

• Tendon injuries are common and can lead to chronic pain and dysfunction.
• Tendon stem cells (TSCs) are crucial for tendon repair and regeneration.
• Understanding the global research landscape of TSCs is vital for advancing therapeutic strategies.

Purpose of the Study:

• To comprehensively analyze the global research status of tendon stem cells.
• To identify current research hotspots and trends in the field of tendon stem cells.
• To provide insights into the most influential publications, institutions, and research themes.

Main Methods:

• Bibliometric analysis using Web of Science Core Collection (WOSCC) data.
• Visualization and analysis using Citespace, Vosviewer, SCImago, and Graphad Prism.
• Identification of publication trends, active countries, key authors, and prominent journals.

Main Results:

• China and the United States are the most active countries in tendon stem cell research.
• Key research hotspots include scaffolds, molecular mechanisms, and inflammation regulation.
• Significant contributions were made by authors affiliated with institutions like the Hong Kong Hospital Authority and the University of Pittsburgh.

Conclusions:

• Tendon stem cells show great promise for tendon tissue engineering applications.
• Further research into scaffolds, molecular mechanisms, and inflammation is warranted.
• The findings highlight the dynamic and evolving nature of tendon stem cell research.