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Strategies for Assessing Autistic-Like Behaviors in Mice
Published on: September 20, 2024
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[Biochemical markers of autism]
I G Samoilova1, M V Matveeva1, D E Galyukova1
1Siberian State Medical University, Tomsk, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|January 23, 2024
Summary
Autism spectrum disorder (ASD) diagnosis is challenging due to behavioral observation subjectivity. This review explores emerging biological biomarkers to improve early and accurate ASD detection and treatment.
Area of Science:
- Neuroscience
- Developmental Biology
- Genetics
Background:
- Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with increasing prevalence.
- Current ASD diagnosis relies on behavioral observation, which presents significant challenges in accuracy and objectivity.
- The need for reliable biomarkers is critical for early detection and effective intervention.
Conclusions:
- Biomarkers hold significant promise for objective ASD diagnosis, moving beyond subjective behavioral assessments.
- Further research is essential to validate and translate these biomarkers into clinical practice.
- Development of reliable biomarkers could revolutionize early detection, intervention, and personalized treatment strategies for ASD.
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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
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