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Updated: Jul 5, 2025

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Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
Published on: January 29, 2011
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Prehospital Use of Waveform Capnography in Intubated Neonates
Krista Hartmann1, Brittney Calatayud1, Avram Flamm1,2,3
1Penn State College of Medicine, Hershey, Pennsylvania.
Prehospital Emergency Care
|January 23, 2024
Summary
Continuous end-tidal carbon dioxide (ETCO2) monitoring for endotracheal tube placement is underused in neonates compared to older patients in prehospital care. This highlights a potential gap in the standard of care for intubated infants.
Area of Science:
- Emergency Medicine
- Pediatric Critical Care
- Anesthesiology
Background:
- Continuous waveform capnography is standard for monitoring endotracheal tube (ETT) placement in adults.
- Neonatal intubation presents challenges due to low tidal volumes and the bulk of capnography equipment, risking ETT dislodgement.
- A potential disparity in care exists for intubated neonates compared to adults regarding continuous ETT monitoring.
Purpose of the Study:
- To investigate the utilization of continuous end-tidal carbon dioxide (ETCO2) monitoring in intubated neonates versus other age groups in the prehospital setting.
- To identify potential gaps in the standard of care for neonatal endotracheal tube placement verification.
Main Methods:
- Retrospective chart review of intubated patients (neonates, children, adolescents, adults) from a single air medical agency.
- Data collected included intubation attempts, success, and capnography use.
- Statistical analysis using Chi Square Goodness of Fit Tests.
Main Results:
- Continuous waveform ETCO2 monitoring was used in 62% of successfully intubated neonates, significantly less than children (94%), adolescents (95%), and adults (97%).
- Statistically significant differences in capnography use were observed between adults and neonates (p=0.013) and among neonates, children, and adolescents (p=0.049).
Conclusions:
- Continuous ETCO2 monitoring is underutilized in intubated neonates in the prehospital setting, indicating a gap in the standard of care.
- Further research is needed to confirm these findings across the industry and assess the impact on undetected ETT displacement in neonates.
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