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Updated: Jul 5, 2025

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
A case of angioimmunoblastic T-cell lymphoma presenting with migration of lung shadows
Tomoya Maruyama1, Takashi Ishiguro1, Kenji Takano1
1Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Abstract:
A 62-year-old woman presented with chronic cough. Chest CT showed multiple nodules and consolidation. Bronchoscopy could not confirm a specific diagnosis. Because her symptoms and lung opacities improved spontaneously, she was followed without treatment. Seven months later, chest radiography showed worsening of consolidation and a tumorous shadow. After performing cervical lymph node and lung tissue biopsies, we diagnosed her as having angioimmunoblastic T-cell lymphoma (AITL). Cases of AITL showing migration of lung shadows have not been reported. AITL development is influenced by immunodeficiency and reactivation of EBV, and migration of lung opacities may be related to the patient's immune status.
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