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Magnesium Decreases Urine Supersaturation but Not Calcium Oxalate Stone Formation in Genetic Hypercalciuric

Qiaoli Li1,2, Nancy S Krieger3, Lee Yang4

  • 1Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA, qiaoli.li@jefferson.edu.

Nephron
|January 23, 2024
PubMed
Summary

Increased dietary magnesium in hypercalciuric rats reduced urine supersaturation but did not prevent calcium oxalate (CaOx) stone formation. This suggests magnesium may influence stone risk factors but not directly inhibit stone development in this model.

Keywords:
Calcium oxalateGenetic hypercalciuric stone-forming ratsKidney stoneMagnesiumUrine supersaturation

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