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Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
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Engaging community pharmacies in practice-based research: Lessons from opioid-focused research.

Nicholas Cox1, Kenneth C Hohmeier2, Alina Cernasev2

  • 1University of Utah College of Pharmacy, United States.

Research in Social & Administrative Pharmacy : RSAP
|January 23, 2024
PubMed
Summary
This summary is machine-generated.

Community pharmacies are vital partners for implementing evidence-based practices through practice-based research. This commentary outlines challenges and offers recommendations for successful research collaborations in community pharmacy settings.

Keywords:
Community pharmacyOpioidsPharmacyPractice-based researchResearch

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Area of Science:

  • Implementation Science
  • Community Pharmacy Practice
  • Practice-Based Research

Background:

  • Translating evidence-based practices into real-world settings is a recognized challenge.
  • Community pharmacies are strategically positioned for practice-based research collaborations.
  • Existing research partnerships face challenges influenced by study type, pharmacy characteristics, and stakeholder engagement.

Purpose of the Study:

  • To identify and describe challenges encountered when partnering with community pharmacies for research.
  • To provide actionable recommendations for mitigating and overcoming these partnership challenges.
  • To leverage authors' experience in opioid-related research collaborations with community pharmacies.

Main Methods:

  • This commentary synthesizes authors' practical experiences.
  • Analysis of challenges in diverse community pharmacy research settings.
  • Development of recommendations based on identified partnership barriers.

Main Results:

  • Challenges vary significantly based on study specifics and pharmacy context.
  • Key areas for improvement include team structure and communication strategies.
  • Effective research integration requires attention to tools, motivation, workflow, and sustainability.

Conclusions:

  • Addressing identified challenges can enhance community pharmacy research partnerships.
  • Implementing the proposed recommendations can facilitate successful practice-based research.
  • Strengthened collaborations are essential for advancing evidence-based practice in community pharmacy.