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Effective and simple interventions to improve outcomes for preterm infants worldwide: The FIGO PremPrep-5 initiative

Megan Hall1, Catalina M Valencia2,3, Priya Soma-Pillay4,5

  • 1Department of Women and Children's Health, St Thomas' Hospital, King's College London, London, UK.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
|January 24, 2024
PubMed

Insights

Preterm birth is a leading cause of infant mortality. The FIGO PremPrep-5 initiative promotes simple, cost-effective interventions like antenatal corticosteroids and kangaroo care to improve survival rates globally.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatology
  • Global Health

Background:

  • Preterm birth is the primary cause of death in children under five globally.
  • Existing interventions for preterm birth complications are not universally applicable.
  • There is a need for accessible, evidence-based strategies to reduce preterm birth mortality.

Purpose of the Study:

  • To introduce the FIGO PremPrep-5 initiative.
  • To disseminate simple, effective interventions for preterm birth care.
  • To promote global implementation of evidence-based preterm birth strategies.

Main Methods:

  • The FIGO PremPrep-5 initiative focuses on five key interventions.
  • Recommendations include antenatal corticosteroids and magnesium sulfate before delivery.
  • Postnatal care emphasizes delayed cord clamping, early breast milk feeding, and kangaroo care.

Main Results:

  • The initiative identifies clinically effective and inexpensive interventions.
  • These methods are designed for broad applicability across various settings.
  • Dissemination tools like training videos and infographics are utilized.

Conclusions:

  • The FIGO PremPrep-5 initiative offers a scalable approach to reducing preterm birth mortality.
  • Simple, cost-effective interventions can significantly improve outcomes for preterm infants.
  • Global adoption of these practices can enhance neonatal survival and quality of life.

Keywords:
antenatal steroidsbreast milkdelayed cord clampingkangaroo carelow‐ and middle‐income countriesmagnesium sulfateprematuritypreterm birth

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