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Persistent Monkeypox-Associated Keratouveitis in a Post-LASIK Cornea: A Case Report With Flap Removal
María Rosell Domínguez1, Jorge Hernández-Cerdá, Víctor Alegre-Ituarte
1Doctor Peset University Hospital, Valencia, Spain.
Cornea
|January 24, 2024
Summary
Mpox virus can cause persistent keratouveitis, even in immunocompetent individuals with prior laser-assisted in situ keratomileusis (LASIK). Management requires a multidisciplinary approach including antiviral therapy and surgery.
Area of Science:
- Ophthalmology
- Virology
- Infectious Diseases
Background:
- Mpox virus (formerly monkeypox) infection can present with diverse clinical manifestations.
- Ocular involvement in mpox is rare but can be severe, particularly in patients with prior ocular surgery.
- Keratouveitis, inflammation of the cornea and anterior uvea, poses a significant challenge in diagnosis and management.
Conclusions:
- Mpox-associated keratouveitis is a rare but serious complication that can occur in immunocompetent patients with a history of LASIK.
- Successful management necessitates a combination of antiviral therapy, anti-inflammatory agents, and surgical intervention.
- This case underscores the need for a multidisciplinary approach and vigilance in diagnosing and treating ocular mpox infections.

