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[Acute myocardial infarction without obstructive coronary disease secondary to thyrotoxicosis due to toxic

Harvey Julián Mejía Sandoval1, Jorge Mario Palmezano Díaz2

  • 1Universidad Industrial de Santander. Departamento de Medicina Interna. Grupo GERMINA. Hospital Universitario de Santander. Bucaramanga, Colombia. Universidad Industrial de Santander Universidad Industrial de Santander Departamento de Medicina Interna Grupo GERMINA Bucaramanga Colombia.

Archivos Peruanos De Cardiologia Y Cirugia Cardiovascular
|January 25, 2024
PubMed

Insights

Myocardial infarction in the absence of obstructive coronary artery disease (MINOCA) can be challenging. This case highlights severe hyperthyroidism as a cause, resolved by treating the underlying thyroid condition.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Myocardial infarction with non-obstructive coronary arteries (MINOCA) presents a diagnostic challenge.
  • An ischemic substrate must be documented for diagnosis and etiology-specific treatment.
  • Altered oxygen supply/demand ratio can cause MINOCA.

Observation:

  • A patient with severe hyperthyroidism and thyrotoxicosis developed acute coronary syndrome.
  • Coronary angiography revealed normal coronary arteries.
  • Cardiac biomarkers showed elevated troponin T.

Findings:

  • Treatment focused on the underlying cause (hyperthyroidism) via medication and surgery.
  • The patient experienced symptomatic improvement and resolution of the condition.
  • Cardiac biomarkers decreased post-treatment.

Implications:

  • Severe hyperthyroidism is a potential cause of MINOCA.
  • Addressing the underlying etiology is crucial for managing MINOCA.
  • This case underscores the importance of considering non-atherosclerotic causes in MINOCA.

Keywords:
Acute myocardial infarctionChest painMyocardial ischemiaThyrotoxicosis

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