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Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

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Published on: May 4, 2011

Relationship between emotion recognition and cognition in multiple sclerosis: a meta-analysis protocol.

Béatrice Degraeve¹, Audrey Henry², Bruno Lenne¹

¹FLSH/ETHICS (EA7446), Lille Catholic University, Lille, France.

BMJ Neurology Open

|January 25, 2024

Summary

This meta-analysis protocol investigates the link between emotion recognition and cognitive deficits in multiple sclerosis (MS). Findings will clarify if social cognition impairments in MS stem from general cognitive dysfunction or are distinct symptoms.

Keywords:

Multiple sclerosis cognitive impairment emotion recognition meta-analysis social cognition

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Last Updated: Jul 5, 2025

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

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Published on: May 4, 2011

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

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Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Published on: February 1, 2012

Area of Science:

Neuroscience
Psychology
Clinical Medicine

Background:

Multiple sclerosis (MS) presents with diverse symptoms, including cognitive and socio-cognitive deficits.
Emotion-recognition impairments are increasingly noted in MS, prompting research into their relationship with general cognitive dysfunction.

Purpose of the Study:

To outline a meta-analysis protocol to clarify the association between emotion recognition and cognitive impairment in MS.
To investigate the relationship across specific cognitive domains (IPS, executive functions, episodic memory) and emotion scores.

Main Methods:

A meta-analysis will be conducted to estimate effect sizes for the association between emotion recognition and cognitive impairment in MS.
Meta-regression analyses will explore heterogeneity based on clinical characteristics like disease duration, MS phenotype, depression, and disability.

Main Results:

The study aims to provide combined effect sizes for emotion recognition and cognitive impairment in MS.
It will identify potential moderators of this association, such as clinical characteristics of patients.

Conclusions:

This research will elucidate whether emotion-recognition deficits in MS are linked to broader cognitive dysfunction or represent independent symptoms.
Findings will inform targeted therapeutic strategies for MS patients.