Management of intra-abdominal lymphomas

Fifty-nine patients (mean age 65) were evaluated for intra-abdominal lymphomas, localized or disseminated, during the period between 1977 and 1985. These lymphomas were lymphocytic (66%), histiocytic (17%), follicular (10%), and mixed (7%). Liver and retroperitoneal nodes were most frequently involved (32%), followed by stomach (31%), bowel (17%), and spleen (20%). Thirty-five patients (59%) underwent some type of surgical procedure supplemented by either chemo- or radiation therapy. Curative and palliative resections accounted for 40 per cent and 26 per cent, respectively while diagnostic laparotomy with or without staging accounted for 34 per cent. The 1-month postoperative mortality was 20 per cent. The 5-year survival was 12 per cent for the surgical group and 0 per cent for the medical group (P less than 0.05). Patients with lymphomas of the stomach and spleen, treated surgically, fared better than their medical counterparts. Most patients in this series died of their disease (55%) or from attempts to eradicate it.