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Spinal Cord Ischemia after Lumbar Artery Embolization for Retroperitoneal Hemorrhage

Stavros Grigoriadis1, Eleni Georgiadi1, Theodoros A Sidiropoulos2

  • 1Interventional Radiology Unit, 2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, "Attikon" University General Hospital, Athens, Greece.

Journal of Vascular and Interventional Radiology : JVIR
|January 25, 2024
PubMed
Abstract

No abstract available in PubMed .

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Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

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