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The Cochlea

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

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Related Experiment Video

Updated: Jul 4, 2025

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

Electrically Evoked Auditory Brainstem Response Using Extracochlear Stimulation at Different Cochlear Sites: A

Woongsang Sunwoo¹, Woonhoe Goo², Seung-Ha Oh²

¹Department of Otorhinolaryngology-Head and Neck Surgery, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.

Clinical and Experimental Otorhinolaryngology

|January 26, 2024

Summary

Extracochlear auditory brainstem response (eEABR) tests correlate with spiral ganglion neuron (SGN) function, offering a way to estimate SGN extent before cochlear implantation.

Keywords:

Cochlear Implants Electric Stimulation Evoked Potentials, Auditory Brain Stem Spiral Ganglion

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Last Updated: Jul 4, 2025

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice

Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice

Published on: May 10, 2019

Optogenetic Stimulation of the Auditory Nerve

Optogenetic Stimulation of the Auditory Nerve

Published on: October 8, 2014

Area of Science:

Neuroscience
Auditory Neuroscience
Otoacoustic Emissions

Background:

Spiral ganglion neurons (SGNs) are crucial for hearing.
Assessing SGN distribution and excitability preoperatively is vital for cochlear implant success.
Electrically evoked auditory brainstem response (EABR) is used to evaluate SGNs.

Purpose of the Study:

To investigate extracochlear EABR (eEABR) as a preoperative tool.
To estimate the distribution and extent of excitable SGNs.
To correlate eEABR with EABR and auditory thresholds.

Main Methods:

Used Sprague-Dawley rats (normal hearing and partially deafened).
Performed extracochlear and intracochlear electrode placements for eEABR and EABR recordings.
Compared slope characteristics, auditory thresholds, and SGN density.

Main Results:

eEABR slopes correlated with EABR slopes in normal-hearing rats.
Auditory thresholds correlated with eEABR slopes in partially deaf rats.
Stimulation region impacted eEABR slopes based on neural condition.

Conclusions:

eEABR slopes show spatial correlation with auditory nerve functionality.
eEABR testing at various cochlear positions can estimate excitable SGN extent.
eEABR is a promising preoperative test for cochlear implant candidates.