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Related Experiment Videos

Outcome and function following prolonged mechanical ventilation.

J E Spicher, D P White

    Archives of Internal Medicine
    |March 1, 1987
    PubMed
    Summary
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    Patients requiring prolonged mechanical ventilation (PMV) have limited survival and poor functional outcomes. Age and pre-illness functional status significantly impact survival, with neurologic and postoperative causes faring better than cardiac or pulmonary ones.

    Area of Science:

    • Critical Care Medicine
    • Pulmonology
    • Neurosurgery

    Background:

    • Prolonged mechanical ventilation is common, yet outcomes data are scarce.
    • Understanding survival and functional status is crucial for this patient group.

    Purpose of the Study:

    • To evaluate the survival rates and functional status of patients requiring prolonged mechanical ventilation.
    • To identify predictors of survival in this population.

    Main Methods:

    • Retrospective review of 250 consecutive patients.
    • Minimum of ten days of ventilatory support analyzed over a five-year period.

    Main Results:

    • Overall survival: 39.2% at discharge, 28.6% at one year, 22.5% at two years.

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  • Predictors of survival: Age and pre-respiratory failure functional status.
  • Highest survival: Postoperative or neurologic disease; Worst prognosis: Cardiac and pulmonary disease.
  • Among survivors, 39.6% institutionalized, 32.7% homebound.

    • Conclusions:

    • Prolonged mechanical ventilation is associated with limited survival.
    • Survivors often experience poor functional status, including institutionalization or home confinement.
    • Prognosis varies significantly based on the underlying cause of respiratory failure and patient's prior condition.