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Updated: Jul 4, 2025

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
Published on: August 25, 2021
Targeted Therapeutic Strategies for the Treatment of Cancer
Benjamin Victoir1, Cécile Croix1, Fabrice Gouilleux2
1INSERM UMR 1100 CEPR, Equipe "Mécanismes Protéolytiques Dans L'inflammation", Faculté de Médecine, 10 Boulevard Tonnellé, BP 3223, 37032 Tours Cedex 01, France.
Abstract:
Extensive research is underway to develop new therapeutic strategies to counteract therapy resistance in cancers. This review presents various strategies to achieve this objective. First, we discuss different vectorization platforms capable of releasing drugs in cancer cells. Second, we delve into multitarget therapies using drug combinations and dual anticancer agents. This section will describe examples of multitarget therapies that have been used to treat solid tumors.
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