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Ionic Liquids in Pharmaceutical and Biomedical Applications: A Review
Yue Zhuo1, He-Li Cheng2, Yong-Gang Zhao3,4
1School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 511442, China.
Pharmaceutics
|January 26, 2024
Summary
Ionic liquids (ILs) offer unique properties for pharmaceutical and biomedical applications. This review details their advancements in drug synthesis, delivery, and stabilization, highlighting their potential to overcome medical challenges.
Area of Science:
- Pharmaceutical Science
- Biomedical Engineering
- Materials Science
Background:
- Ionic liquids (ILs) possess unique properties like tunable structures, solubility, and stability.
- These properties make ILs suitable for diverse pharmaceutical and biomedical applications.
- ILs can address challenges such as poor drug solubility and inefficient delivery.
Purpose of the Study:
- To systematically analyze recent advancements and applications of ILs in the pharmaceutical field.
- To explore the use of ILs in drug synthesis, analysis, solubilization, and crystal engineering.
- To investigate the role of ILs in biomedical applications including drug carriers and protein stabilization.
Main Methods:
- Literature review of recent advancements in ILs for pharmaceutical and biomedical fields.
- Analysis of IL applications in drug synthesis, analysis, solubilization, and crystal engineering.
- Exploration of ILs in drug delivery, protein stabilization, antimicrobials, and bioactive applications.
Main Results:
- ILs enhance chemical reaction processes, improve yields, and reduce pollution.
- ILs effectively address issues like poor drug solubility and low drug delivery efficiency.
- ILs show promise as drug carriers, protein stabilizers, antimicrobials, and in bioactive formulations.
Conclusions:
- Ionic liquids are versatile materials with significant potential in pharmaceutical and biomedical sectors.
- Further research into ILs can lead to improved drug development and therapeutic strategies.
- ILs offer innovative solutions for enhancing drug efficacy and patient outcomes.

