Integrated Microfluidic Chip Technology for Copper Ion Detection Using an All-Solid-State Ion-Selective Electrode

Area of Science:

• Electrochemistry
• Materials Science
• Analytical Chemistry

Background:

• All-solid-state ion-selective electrodes (ASS-ISEs) are crucial for electrochemical sensing.
• Developing reliable copper ion detection methods is essential for various applications.
• Poly(3,4-ethylenedioxythiophene) and polystyrene sulfonate (PEDOT/PSS) offers promising properties for electrode modification.

Purpose of the Study:

• To prepare and characterize an all-solid-state ion-selective electrode (ASS-ISE) for copper ions.
• To design and integrate a microfluidic chip with the ASS-ISE for enhanced analysis.
• To develop and validate a microfluidic chip test system for accurate copper ion quantification.

Main Methods:

• Electrode deposition was used to create a poly(3,4-ethylenedioxythiophene) and polystyrene sulfonate (PEDOT/PSS) conversion layer on the ASS-ISE.
• Morphological characterization of the PEDOT/PSS film was performed.
• A microfluidic chip was designed, prepared, and integrated with the ASS-ISE.
• A self-constructed potential detection device was utilized for the integrated system.
• Atomic absorption spectrophotometry (AAS) was employed for comparative validation.

Main Results:

• The morphology of the PEDOT/PSS film was characterized.
• The performance of the copper ion-selective film was optimized.
• An integrated microfluidic chip test system with the ASS-ISE was successfully developed.
• The system's accuracy was validated against atomic absorption spectrophotometry (AAS).
• The relative standard deviation (RSD) of the integrated system was 4.54%.

Conclusions:

• The developed integrated microfluidic chip test system with an ASS-ISE for copper ions is accurate and reliable.
• The system's performance, with an RSD of 4.54%, meets the industry standard requirement (RSD ≤ 5% in DL/T 955-2016).
• This ASS-ISE and microfluidic chip integration offers a promising approach for precise copper ion analysis.