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Mood disorder and multiple sclerosis.

R T Joffe, G P Lippert, T A Gray

    Archives of Neurology
    |April 1, 1987
    PubMed
    Summary
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    Many multiple sclerosis patients experience mental health issues, with a significant portion having depression or manic-depressive illness. These psychiatric disorders are common in multiple sclerosis (MS) care.

    Area of Science:

    • Neurology
    • Psychiatry

    Background:

    • Multiple sclerosis (MS) is a chronic neurological disease.
    • Psychiatric disorders are frequently observed in patients with MS.

    Purpose of the Study:

    • To systematically evaluate the prevalence of psychiatric disorders in patients with multiple sclerosis (MS).
    • To explore the relationship between psychiatric conditions and neurologic dysfunction in MS.

    Main Methods:

    • A systematic psychiatric evaluation was conducted.
    • 100 consecutive patients at a multiple sclerosis clinic were assessed.

    Main Results:

    • 42% of patients had a lifetime history of depression.
    • 13% met criteria for manic-depressive illness.

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  • Only 28% had no psychiatric diagnosis.

    • Conclusions:

    • Psychiatric disorders are highly prevalent in multiple sclerosis patients.
    • Findings highlight the need for integrated care addressing both neurologic and psychiatric aspects of MS.