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Enhanced detection of acrylamide using a versatile solid-state upconversion sensor through spectral and visual

Yawen Rong1, Md Mehedi Hassan2, Jizhong Wu3

  • 1School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, 310023, PR China.

Journal of Hazardous Materials
|January 26, 2024
PubMed
Summary
This summary is machine-generated.

A new solid-state luminescence sensor detects acrylamide (AM), a potential carcinogen formed during high-temperature food processing. This sensor offers accurate, on-site detection using smartphone technology.

Keywords:
AcrylamideFluorescence resonance energy transferSolid-phase sensorUpconversion nanoparticlesVisual monitoring

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Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Nanotechnology

Background:

  • Acrylamide (AM) is a potential carcinogen formed during high-temperature food processing.
  • Existing detection methods can be complex and time-consuming.
  • Development of rapid, on-site detection methods is crucial for food safety.

Purpose of the Study:

  • To develop a maneuverable solid-state luminescence sensor for acrylamide detection.
  • To utilize upconversion nanoparticles and aptamer-functionalized polydimethylsiloxane (PDMS) for sensing.
  • To enable both spectral and visual monitoring of acrylamide levels.

Main Methods:

  • Encapsulating core-shell upconversion nanoparticles in PDMS.
  • Modifying PDMS with AM aptamer and fluorescein isothiocyanate isomer (FITC).
  • Utilizing fluorescence resonance energy transfer (FRET) for luminescence quenching and recovery.

Main Results:

  • The sensor demonstrated a low detection limit (LOD) of 1.00 nM (spectral) and 1.07 nM (visual).
  • Accurate results were obtained in actual foodstuff detection, comparable to standard methods.
  • The sensor showed potential for on-site monitoring via smartphone integration.

Conclusions:

  • The developed solid-state luminescence sensor offers a sensitive and accurate method for acrylamide detection.
  • Its maneuverability and smartphone compatibility facilitate on-site food safety monitoring.
  • This technology holds promise for improving the safety and quality of processed foods.