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Related Experiment Video

Updated: Jul 6, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

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Amount of Gleason Pattern 3 Is Not Predictive of Risk in Grade Group 2-4 Prostate Cancer.

Andrew J Vickers1, Melissa Assel1, Matthew R Cooperberg2

  • 1Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

European Urology
|January 26, 2024
PubMed
Summary
This summary is machine-generated.

Quantifying the amount of Gleason pattern 4, not its proportion, better predicts adverse pathology in localized prostate cancer. This improves grade group assignment for treatment decisions.

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Accurate grading of prostate cancer is crucial for treatment decisions.

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  • Gleason grading, based on patterns of cancer cell growth, is a key prognostic factor.
  • Current grading systems may not optimally capture the predictive value of Gleason pattern 4.