Related Experiment Video
Updated: Jun 27, 2026
07:12
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
3.5K
Ultrasound-based quantitative tools in predicting renal involvement in asymptomatic primary hyperparathyroidism
B Candemir1, F Cuce2, S Akın3
1Gulhane Faculty of Medicine, Department of Endocrinology and Metabolism, University of Health Sciences, Keçiören, 06010, Ankara, Turkey. bilalogluburcu@gmail.com.
Journal of Endocrinological Investigation
|January 27, 2024
Summary
Acoustic radiation force impulse (ARFI) imaging and renal resistive index (RRI) can detect kidney changes in patients with asymptomatic primary hyperparathyroidism (aPHPT). These methods help identify renal impairment early for better patient management.
Area of Science:
- Nephrology
- Endocrinology
- Medical Imaging
Background:
- Asymptomatic primary hyperparathyroidism (aPHPT) is linked to renal complications.
- Early detection of renal impairment indicators is crucial for proactive management in aPHPT patients.
Purpose of the Study:
- To evaluate the effectiveness of acoustic radiation force impulse (ARFI) imaging and renal resistive index (RRI) in detecting renal parenchymal and vascular changes in aPHPT patients.
Main Methods:
- The study included 42 aPHPT patients and 42 matched controls.
- Renovascular changes were assessed using RRI with Doppler ultrasonography.
- Renal parenchymal changes were evaluated by ARFI quantification (shear wave velocity - SWV).
Main Results:
- Patients with aPHPT showed significantly higher mean RRI and SWV compared to controls.
- SWV correlated with serum calcium, parathyroid hormone (PTH), and adenoma size.
- RRI correlated positively with serum calcium and PTH levels.
Conclusions:
- ARFI imaging and RRI measurements show promise in identifying renal involvement in aPHPT.
- These imaging techniques can aid in the early detection of kidney complications in aPHPT.
Related Concept Videos
01:17Ultrasonography
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
During an ultrasonography procedure, a handheld device called a...
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
01:22Nursing Assessment of the Genitourinary System III: Percussion and Auscultation
The genitourinary system maintains the body's fluid balance, waste excretion, and overall homeostasis. Proper assessment is essential for early detection of disorders, with percussion and auscultation integral to this evaluation. These methods help identify signs of kidney or bladder issues and provide important diagnostic clues.Percussion for Kidney TendernessPercussion is used to assess tenderness and detect kidney and bladder abnormalities. A common method for determining kidney tenderness...
01:24Imaging Studies II: Ultrasonography
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
01:22Imaging Studies V: Intravenous Urography and Retrograde Pyelography
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...