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The evolutionary dynamics of hyperparasites.

Graham R Northrup1, Andy White2, Steven R Parratt3

  • 1Center for Computational Biology, College of Engineering, University of California, Berkeley, CA, USA.

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|January 27, 2024
PubMed
Summary
This summary is machine-generated.

Hyperparasites, parasites of parasites, evolve reduced virulence when hitchhiking with their hosts. This evolutionary dynamic impacts parasite virulence and multitrophic interactions.

Keywords:
Adaptive dynamicsBiocontrolEvolutionary theoryHyperparasite

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Area of Science:

  • Evolutionary biology
  • Ecology
  • Microbiology

Background:

  • Evolutionary theory traditionally focuses on pairwise interactions (e.g., host-parasite).
  • Complex interactions involving hyperparasites (parasites of parasites) are less studied.
  • Hyperparasites are prevalent, including viruses like CHV-1 and bacteriophages.

Purpose of the Study:

  • To develop a general modeling framework for hyperparasite evolution.
  • To investigate the role of hyperparasite transmission with its parasite host.
  • To analyze the influence of host and parasite traits on hyperparasite evolution.

Main Methods:

  • General modeling framework construction.
  • Analysis of hyperparasite transmission dynamics ('hitchhiking').
  • Examination of trait impacts (virulence, infection acuity) on hyperparasite evolution.

Main Results:

  • Hyperparasites hitchhiking with their hosts evolve lower virulence, potentially leading to hypermutualism or hypercommensalism.
  • High parasite virulence selects for increased hyperparasite virulence, reducing overall parasite virulence.
  • Acute parasite infection also selects for increased hyperparasite virulence.

Conclusions:

  • Hyperparasite evolution is significantly shaped by their mode of transmission.
  • Hyperparasites can influence parasite virulence and host-parasite dynamics.
  • Understanding multitrophic interactions is crucial for evolutionary and ecological insights.