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Prolonged hiccups induced by renal infarction: a case report
Akira Kato1, Nobuhiro Sato2, Yasuo Hirose2
1Department of Emergency and Critical Care Medicine, Niigata City General Hospital, 463-7 Shumoku, Chuo-Ku, Niigata, Niigata, 950-1197, Japan. akirakatou989898@gmail.com.
Journal of Medical Case Reports
|January 27, 2024
Summary
Prolonged hiccups may signal underlying renal infarction. This case report highlights the importance of considering kidney disease in patients with persistent hiccups, especially when other causes are ruled out.
Area of Science:
- Nephrology
- Gastroenterology
Background:
- Hiccups are typically transient, resolving within 48 hours.
- Prolonged hiccups warrant investigation for underlying pathologies.
- The link between hiccups and renal infarction is not well-established.
Observation:
- An 87-year-old male with atrial fibrillation and on antithrombotic therapy presented with prolonged hiccups.
- Discontinuation of antithrombotic therapy due to subcortical bleeding preceded right back pain.
- Computed tomography confirmed right renal infarction.
Findings:
- The patient's prolonged hiccups resolved after diagnosis and continuation of antithrombotic therapy for renal infarction.
- Inflammation associated with renal infarction is hypothesized to have stimulated the diaphragm, causing hiccups.
Implications:
- Internal organ diseases, including renal infarction, can trigger diaphragmatic irritation leading to hiccups.
- Renal disease should be considered in the differential diagnosis of prolonged hiccups.
- This case underscores the importance of a comprehensive diagnostic approach for persistent hiccups.

