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Elapid snake bite.

D K Pawar, H Singh

    British Journal of Anaesthesia
    |March 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Elapid snake bites can cause respiratory muscle paralysis. Antivenom and neostigmine showed no significant benefit over artificial ventilation alone for established paralysis.

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    Area of Science:

    • Toxicology
    • Neurology
    • Critical Care Medicine

    Background:

    • Elapid snakebites are a significant cause of envenomation globally.
    • Respiratory muscle paralysis is a life-threatening complication of certain elapid snakebites.
    • Current management often includes antivenom and supportive care.

    Observation:

    • Four patients with elapid snakebite-induced respiratory muscle paralysis were studied.
    • Two patients received antivenom, neostigmine, and artificial ventilation.
    • Two patients received only artificial ventilation.

    Findings:

    • No clinically significant difference in recovery was observed between the two treatment groups.
    • Artificial ventilation alone was as effective as combined therapy for established paralysis.

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  • This suggests potential limitations of antivenom and neostigmine in this specific clinical scenario.

    • Implications:

    • Avoidance of antivenom and neostigmine in established elapid snakebite paralysis may be warranted.
    • Further research is needed to confirm these findings and refine treatment protocols.
    • This could lead to more streamlined and potentially less toxic management strategies for severe snakebite neurotoxicity.