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Benign Acute Childhood Myositis in a Pediatric Patient Post Influenza B Infection
Michael C Huzior1, Brendan P Chernicki1, Lisa Nguyen2
1Pediatrics, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Insights
Benign acute childhood myositis (BACM) is a rare viral complication causing leg pain in children. This case highlights a severe presentation with elevated creatine kinase levels, emphasizing the need for vigilant monitoring and supportive care.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Benign acute childhood myositis (BACM) is a self-limiting condition following viral infections, typically presenting with sudden lower extremity pain.
- It is often associated with influenza outbreaks and characterized by difficulty walking.
- Severe complications like rhabdomyolysis and renal failure are rare but possible without proper management.
Observation:
- A unique case of a five-year-old male with a month-long history of leg pain preceding an upper respiratory infection (URI).
- The patient presented with severe bilateral leg pain and inability to ambulate, following a fever and cough.
- Influenza B was confirmed, and initial creatine kinase (CK) levels exceeded 10,000 U/L, significantly higher than typical BACM cases.
Findings:
- Diagnosis of BACM was established based on clinical presentation and elevated CK levels.
- The patient's CK levels peaked over 13,000 U/L, indicating a more severe myositis than commonly reported.
- Supportive care, including hydration and routine CK monitoring, was initiated.
Implications:
- This case underscores the potential for severe presentations of BACM, even in the absence of trauma.
- Highlights the importance of daily CK monitoring until levels trend downwards and symptoms resolve to prevent complications.
- Suggests that pre-existing myalgia may predispose children to more severe outcomes when exacerbated by viral infections.
Abstract:
Benign acute childhood myositis (BACM) is a mild and self-limited sudden onset of lower extremity pain during or following recovery from a viral illness. It is characterized by difficulty walking due to severe bilateral calf pain, which usually resolves in three days. It is typically appreciated during times of large influenza outbreaks and epidemics. The most severe complication can be rhabdomyolysis without proper treatment and can lead to renal damage and potential renal failure. There are limited reported cases of BACM and therefore no clear guidelines in the treatment or management of the condition. This case is unique in the sense that the patient had leg pain the entire month prior to presentation in the absence of trauma or injury, and it is believed that the pre-existing myalgia may have been exacerbated by an upper respiratory infection (URI) that started a few weeks after the leg pain onset. In addition, this patient's creatine kinase peaked at over 13,000 U/L, which is three to five times higher than the average of other reported children with this condition. The patient is a five-year-old male who presented to the emergency department with bilateral leg pain and difficulty ambulating. His guardian reported that the leg pain began one month prior to presentation and worsened to the point where he could no longer ambulate, following a fever and cough that began one week prior to presentation. A respiratory viral panel was positive for influenza B, and initial creatine kinase (CK) levels were greater than 10,000. A diagnosis of BACM was made, and supportive care was initiated. BACM is an infrequent complication following a viral infection that is typically treatable with hydration management and routine CK monitoring. Symptoms of BACM are usually limited to muscle pain and weakness, but it can progress to rhabdomyolysis and renal failure if not managed properly. It is therefore crucial that physicians monitor CK values daily until a downtrend is noticed and symptoms begin to resolve.
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